COX4I2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
COX4I2 transfected lysate.
Western Blot
Lane 1: COX4I2 transfected lysate ( 20.00 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-COX4I2 full-length
Host
Human
Theoretical MW (kDa)
20
Interspecies Antigen Sequence
Mouse (74); Rat (71)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-COX4I2 antibody (H00084701-D01P) by Western Blots.
SDS-PAGE Gel
COX4I2 transfected lysate.
Western Blot
Lane 1: COX4I2 transfected lysate ( 20.00 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — COX4I2
Entrez GeneID
84701GeneBank Accession#
NM_032609.2Protein Accession#
NP_115998.2Gene Name
COX4I2
Gene Alias
COX4, COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2
Gene Description
cytochrome c oxidase subunit IV isoform 2 (lung)
Omim ID
607976Gene Ontology
HyperlinkGene Summary
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq
Other Designations
OTTHUMP00000030533|cytochrome c oxidase subunit IV isoform 2|cytochrome c oxidase subunit IV-like 2
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Interactome
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Pathway
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Disease
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