NEIL1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of NEIL1 expression in transfected 293T cell line (H00079661-T01) by NEIL1 MaxPab polyclonal antibody.
Lane 1: NEIL1 transfected lysate(42.9 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human NEIL1 protein.
Immunogen
NEIL1 (AAH10876.1, 1 a.a. ~ 390 a.a) full-length human protein.
Sequence
MPEGPELHLASQFVNEACRALVFGGCVEKSSVSRNPEVPFESSAYRISASARGKELRLILSPLPGAQPQQEPLALVFRFGMSGSFQLVPREELPRHAHLRFYTAPPGPRLALCFVDIRRFGRWDLGGKWQPGRGPCVLQEYQQFRENVLRNLADKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARSVLEALQQHRPSPELTLSQKIRTKLQNPDLLELCHSVPKEVVQLGGRGYGSESGEEDFAAFRAWLRCYGMPGMSSLQDRHGRTIWFQGDPGPLAPKGRKSRKKKSKATQLSPEDRVEDALPPSKAPSRTRRAKRDLPKRTATQRPEGTSLQQDPEAPTVPKKGRRKGRQAASGHCRPRKVKADIPSLEPEGTSAS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (78)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NEIL1 expression in transfected 293T cell line (H00079661-T01) by NEIL1 MaxPab polyclonal antibody.
Lane 1: NEIL1 transfected lysate(42.9 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — NEIL1
Entrez GeneID
79661GeneBank Accession#
BC010876.1Protein Accession#
AAH10876.1Gene Name
NEIL1
Gene Alias
FLJ22402, FPG1, NEI1, hFPG1
Gene Description
nei endonuclease VIII-like 1 (E. coli)
Omim ID
608844Gene Ontology
HyperlinkGene Summary
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM
Other Designations
endonuclease VIII|nei endonuclease VIII-like 1
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Interactome
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Pathway
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Disease
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