AICDA 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-AICDA full-length
Host
Human
Theoretical MW (kDa)
24
Interspecies Antigen Sequence
Mouse (92); Rat (93)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-AICDA antibody (H00057379-D01P) by Western Blots.
SDS-PAGE Gel
AICDA transfected lysate.
Western Blot
Lane 1: AICDA transfected lysate ( 24.00 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — AICDA
Entrez GeneID
57379GeneBank Accession#
NM_020661.1Protein Accession#
AAH06296.1Gene Name
AICDA
Gene Alias
AID, ARP2, CDA2, HIGM2
Gene Description
activation-induced cytidine deaminase
Gene Ontology
HyperlinkGene Summary
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq
Other Designations
activation-induced deaminase|integrated into Burkitt's lymphoma cell line Ramos
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Interactome
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Pathway
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Disease
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