BCOR 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BCOR full-length
Host
Human
Theoretical MW (kDa)
110.55
Interspecies Antigen Sequence
Mouse (88); Rat (89)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BCOR antibody (H00054880-B01) by Western Blots.
SDS-PAGE Gel
BCOR transfected lysate.
Western Blot
Lane 1: BCOR transfected lysate ( 110.55 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BCOR
Entrez GeneID
54880GeneBank Accession#
NM_020926.2Protein Accession#
NP_065977.1Gene Name
BCOR
Gene Alias
ANOP2, FLJ20285, FLJ38041, KIAA1575, MAA2, MCOPS2, MGC131961, MGC71031
Gene Description
BCL6 co-repressor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
5830466J11Rik|8430401K06Rik|BCL-6 interacting corepressor|OTTHUMP00000025766|OTTHUMP00000025768
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