BSCL2 monoclonal antibody (M01), clone 1G4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant BSCL2.
Immunogen
BSCL2 (NP_116056, 259 a.a. ~ 357 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
WGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAAL
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged BSCL2 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — BSCL2
Entrez GeneID
26580GeneBank Accession#
NM_032667Protein Accession#
NP_116056Gene Name
BSCL2
Gene Alias
GNG3LG, HMN5, MGC4694, SPG17
Gene Description
Bernardinelli-Seip congenital lipodystrophy 2 (seipin)
Gene Ontology
HyperlinkGene Summary
This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
seipin
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Interactome
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Disease
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