COL4A3BP monoclonal antibody (M02), clone 1A1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant COL4A3BP.
Immunogen
COL4A3BP (NP_112729, 499 a.a. ~ 598 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TWIVCNFSVDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged COL4A3BP is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — COL4A3BP
Entrez GeneID
10087GeneBank Accession#
NM_031361Protein Accession#
NP_112729Gene Name
COL4A3BP
Gene Alias
CERT, CERTL, FLJ20597, GPBP, STARD11
Gene Description
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
Omim ID
604677Gene Ontology
HyperlinkGene Summary
This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Goodpasture antigen-binding protein|OTTHUMP00000128248|OTTHUMP00000128249|START domain containing 11|StAR-related lipid transfer (START) domain containing 11|alpha 3 type IV collagen binding protein|ceramide transporter|lipid-transfer protein CERTL
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