IL18BP monoclonal antibody (M05), clone 2A9
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged IL18BP is approximately 3ng/ml as a capture antibody.
Western Blot detection against Immunogen (43.78 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant IL18BP.
Immunogen
IL18BP (AAH44215, 31 a.a. ~ 194 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TPVSQTTTAATASVRSTKDPCPSQPPVFPAAKQCPALEVTWPEVEVPLNGTLSLSCVACSRFPNFSILYWLGNGSFIEHLPGRLWEGSTSRERGSTGTQLCKALVLEQLTPALHSTNFSCVLVDPEQVVQRHVVLAQLWAGLRATLPPTQEALPSSHSSPQQQG
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (43.78 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged IL18BP is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — IL18BP
Entrez GeneID
10068GeneBank Accession#
BC044215Protein Accession#
AAH44215Gene Name
IL18BP
Gene Alias
IL18BPa
Gene Description
interleukin 18 binding protein
Omim ID
604113Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
MC51L-53L-54L homolog gene product|OTTHUMP00000179141|OTTHUMP00000179143
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Disease
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