CLDN1 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of CLDN1 transfected lysate using rabbit polyclonal anti-CLDN1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-CLDN1.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (90)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of CLDN1 transfected lysate using rabbit polyclonal anti-CLDN1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-CLDN1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-CLDN1 (300 ul)
2. Antibody pair for WB: mouse polyclonal anti-CLDN1 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — CLDN1
Entrez GeneID
9076Gene Name
CLDN1
Gene Alias
CLD1, ILVASC, SEMP1
Gene Description
claudin 1
Gene Ontology
HyperlinkGene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq
Other Designations
senescence-associated epithelial membrane protein 1
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Interactome
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Pathway
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Disease
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