XRCC3 MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human XRCC3 protein.
Immunogen
XRCC3 (NP_005423.1, 1 a.a. ~ 346 a.a) full-length human protein.
Sequence
MDLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGSSILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIFIEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASAPRARHLQSLGATLRELSSAFQSPVLCINQVTEAMEEQGAAHGPLGFWDERVSPALGITWANQLLVRLLADRLREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (73); Rat (73)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of XRCC3 expression in transfected 293T cell line (H00007517-T01) by XRCC3 MaxPab polyclonal antibody.
Lane 1: XRCC3 transfected lysate(38.06 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — XRCC3
Entrez GeneID
7517GeneBank Accession#
NM_005432.2Protein Accession#
NP_005423.1Gene Name
XRCC3
Gene Alias
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Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 3
Omim ID
600675Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
DNA repair protein XRCC3|RAD51-like|X-ray repair cross complementing protein 3|X-ray-repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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