TFAP2B monoclonal antibody (M02), clone 2F6
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More Files
- More Functions
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TFAP2B.
Immunogen
TFAP2B (NP_003212, 73 a.a. ~ 182 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TFAP2B expression in transfected 293T cell line by TFAP2B monoclonal antibody (M02), clone 2F6.
Lane 1: TFAP2B transfected lysate(50.474 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to TFAP2B on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — TFAP2B
Entrez GeneID
7021GeneBank Accession#
NM_003221Protein Accession#
NP_003212Gene Name
TFAP2B
Gene Alias
AP-2B, AP2-B, MGC21381
Gene Description
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq
Other Designations
OTTHUMP00000039925|activating enhancer binding protein 2 beta|transcription factor AP-2 beta
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Interactome
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Disease
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