STX1A MaxPab rabbit polyclonal antibody (D01)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human STX1A protein.
Immunogen
STX1A (AAH03011.1, 1 a.a. ~ 251 a.a) full-length human protein.
Sequence
MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQTMWRGPCLTPRRPSSTRARRAGRKS
Host
Rabbit
Reactivity
Human, Mouse, Rat
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
STX1A MaxPab rabbit polyclonal antibody. Western Blot analysis of STX1A expression in rat brain.Western Blot (Tissue lysate)
STX1A MaxPab rabbit polyclonal antibody. Western Blot analysis of STX1A expression in mouse liver.Western Blot (Transfected lysate)
Western Blot analysis of STX1A expression in transfected 293T cell line (H00006804-T02) by STX1A MaxPab polyclonal antibody.
Lane 1: STX1A transfected lysate(29.00 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of STX1A transfected lysate using anti-STX1A MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with STX1A purified MaxPab mouse polyclonal antibody (B01P) (H00006804-B01P). -
Gene Info — STX1A
Entrez GeneID
6804GeneBank Accession#
BC003011.1Protein Accession#
AAH03011.1Gene Name
STX1A
Gene Alias
HPC-1, STX1, p35-1
Gene Description
syntaxin 1A (brain)
Omim ID
186590Gene Ontology
HyperlinkGene Summary
Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM
Other Designations
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Interactome
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Pathway
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Disease
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