PSMD7 MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PSMD7 protein.
Immunogen
PSMD7 (NP_002802, 1 a.a. ~ 324 a.a) full-length human protein.
Sequence
MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKDRKEDKEKDKDKEKSDVKKEEKKEKK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PSMD7 MaxPab polyclonal antibody. Western Blot analysis of PSMD7 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of PSMD7 expression in transfected 293T cell line (H00005713-T01) by PSMD7 MaxPab polyclonal antibody.
Lane 1: PSMD7 transfected lysate(35.64 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PSMD7
Entrez GeneID
5713GeneBank Accession#
NM_002811Protein Accession#
NP_002802Gene Name
PSMD7
Gene Alias
MOV34, P40, Rpn8, S12
Gene Description
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
Omim ID
157970Gene Ontology
HyperlinkGene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. [provided by RefSeq
Other Designations
26S proteasome non-ATPase regulatory subunit 7|26S proteasome regulatory subunit S12|Moloney leukemia virus-34 proviral integration|Mov34 homolog|proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)|proteasome 26S non-ATPase subunit
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Interactome
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Disease
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