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PSMA7 MaxPab mouse polyclonal antibody (B01P) MaxPab

  • Catalog # : H00005688-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human PSMA7 protein.
  • Immunogen:
  • PSMA7 (NP_002783.1, 1 a.a. ~ 248 a.a) full-length human protein.
  • Sequence:
  • MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENEKKKQKKAS
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Interspecies Antigen Sequence:
  • Mouse (99); Rat (99)
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • PSMA7 MaxPab polyclonal antibody. Western Blot analysis of PSMA7 expression in human liver.
  • PDF DownloadProtocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of PSMA7 expression in transfected 293T cell line (H00005688-T01) by PSMA7 MaxPab polyclonal antibody.

    Lane 1: PSMA7 transfected lysate(27.28 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5688
  • Gene Name:
  • PSMA7
  • Gene Alias:
  • C6,HSPC,MGC3755,RC6-1,XAPC7
  • Gene Description:
  • proteasome (prosome, macropain) subunit, alpha type, 7
  • Gene Summary:
  • The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031449,proteasome alpha 7 subunit,proteasome subunit RC6-1,proteasome subunit XAPC7,proteasome subunit alpha 4
  • Gene Pathway
  • Related Disease
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