PROC monoclonal antibody (M01), clone 3A10
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More Files
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Western Blot (Tissue lysate)
PROC monoclonal antibody (M01), clone 3A10. Western Blot analysis of PROC expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of PROC expression in transfected 293T cell line by PROC monoclonal antibody (M01), clone 3A10.
Lane 1: PROC transfected lysate (Predicted MW: 52.1 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PROC transfected lysate using anti-PROC monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PROC MaxPab rabbit polyclonal antibody.
Western Blot detection against Immunogen (36.41 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PROC.
Immunogen
PROC (AAH34377, 32 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFC
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.41 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PROC monoclonal antibody (M01), clone 3A10. Western Blot analysis of PROC expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of PROC expression in transfected 293T cell line by PROC monoclonal antibody (M01), clone 3A10.
Lane 1: PROC transfected lysate (Predicted MW: 52.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of PROC transfected lysate using anti-PROC monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PROC MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — PROC
Entrez GeneID
5624GeneBank Accession#
BC034377Protein Accession#
AAH34377Gene Name
PROC
Gene Alias
PC, PROC1
Gene Description
protein C (inactivator of coagulation factors Va and VIIIa)
Omim ID
176860Gene Ontology
HyperlinkGene Summary
The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM
Other Designations
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Interactome
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