NOV (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human NOV full-length ORF ( AAH15028, 1 a.a. - 357 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDEGSGLYCDRSADPSKQTGICTAVEGDNCVFDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
65.01
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NOV
Entrez GeneID
4856GeneBank Accession#
BC015028Protein Accession#
AAH15028Gene Name
NOV
Gene Alias
CCN3, IGFBP9
Gene Description
nephroblastoma overexpressed gene
Omim ID
164958Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq
Other Designations
nephroblastoma overexpressed
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Interactome
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Publication Reference
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Roles of heterotypic CCN2/CTGF-CCN3/NOV and homotypic CCN2-CCN2 interactions in expression of the differentiated phenotype of chondrocytes.
Hoshijima M, Hattori T, Aoyama E, Nishida T, Yamashiro T, Takigawa M.
The FEBS Journal 2012 Oct; 279(19):3584.
Application：Func, PI, Recombinant protein.
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Novel effects of CCN3 that may direct the differentiation of chondrocytes.
Janune D, Kubota S, Nishida T, Kawaki H, Perbal B, Iida S, Takigawa M.
FEBS Letters 2011 Oct; 585(19):3033.
Application：Func, Rat, Rat epiphyseal chondrocytes.
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Roles of heterotypic CCN2/CTGF-CCN3/NOV and homotypic CCN2-CCN2 interactions in expression of the differentiated phenotype of chondrocytes.
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