KLRC1 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human KLRC1 protein.
Immunogen
KLRC1 (NP_002250.1, 1 a.a. ~ 233 a.a) full-length human protein.
Sequence
MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of KLRC1 expression in transfected 293T cell line (H00003821-T02) by KLRC1 MaxPab polyclonal antibody.
Lane 1: KLRC1 transfected lysate(26.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — KLRC1
Entrez GeneID
3821GeneBank Accession#
NM_002259Protein Accession#
NP_002250.1Gene Name
KLRC1
Gene Alias
CD159A, MGC13374, MGC59791, NKG2, NKG2A
Gene Description
killer cell lectin-like receptor subfamily C, member 1
Omim ID
161555Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq
Other Designations
C-lectin type II protein|NK cell receptor A|NKG2-1/B activating NK receptor|NKG2-A/B type II integral membrane protein|natural killer cell lectin|natural killer group protein 2
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Interactome
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Disease
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