HLA-DOA (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human HLA-DOA partial ORF ( NP_002110.1, 28 a.a. - 125 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ADHMGSYGPAFYQSYGASGQFTHEFDEEQLFSVDLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPKSRVEL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HLA-DOA
Entrez GeneID
3111GeneBank Accession#
NM_002119Protein Accession#
NP_002110.1Gene Name
HLA-DOA
Gene Alias
HLA-DNA, HLA-DZA, HLADZ
Gene Description
major histocompatibility complex, class II, DO alpha
Omim ID
142930Gene Ontology
HyperlinkGene Summary
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq
Other Designations
HLA-D0-alpha|MHC class II antigen|OTTHUMP00000029303|lymphocyte antigen|major histocompatibility complex, class II, DN alpha
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Interactome
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Pathway
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Disease
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