HLA-DMA purified MaxPab rabbit polyclonal antibody (D01P)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human HLA-DMA protein.
Immunogen
HLA-DMA (NP_006111.2, 1 a.a. ~ 261 a.a) full-length human protein.
Sequence
MGHEQNQGAALLQMLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADWAQEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEVFTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPVEGFGPTFVSAVDGLSFQAFSYLNFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALPSDLLENVLCGVAFGLGVLGIIVGIVLIIYFRKPCSGD
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Tissue lysate)
HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in mouse kidney.Western Blot (Tissue lysate)
HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in human stomach.Western Blot (Cell lysate)
HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in Jurkat.Western Blot (Cell lysate)
HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of HLA-DMA expression in transfected 293T cell line (H00003108-T01) by HLA-DMA MaxPab polyclonal antibody.
Lane 1: HLA-DMA transfected lysate(29.20 KDa).
Lane 2: Non-transfected lysate.
-
Gene Info — HLA-DMA
Entrez GeneID
3108GeneBank Accession#
NM_006120Protein Accession#
NP_006111.2Gene Name
HLA-DMA
Gene Alias
D6S222E, DMA, HLADM, RING6
Gene Description
major histocompatibility complex, class II, DM alpha
Omim ID
142855Gene Ontology
HyperlinkGene Summary
HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq
Other Designations
OTTHUMP00000029242|OTTHUMP00000062997|class II histocompatibility antigen, M alpha chain
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
The non-classical major histocompatibility complex II protein SLA-DM is crucial for African swine fever virus replication.
Katrin Pannhorst, Jolene Carlson, Julia E Hölper, Finn Grey, John Kenneth Baillie, Dirk Höper, Elisabeth Wöhnke, Kati Franzke, Axel Karger, Walter Fuchs, Thomas C Mettenleiter.
Scientific Reports 2023 Aug; 13(1):10342.
Application:WB, Human, HEK-293 T cells.
-
The non-classical major histocompatibility complex II protein SLA-DM is crucial for African swine fever virus replication.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com