GZMB purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Western Blot (Tissue lysate)
GZMB MaxPab rabbit polyclonal antibody. Western Blot analysis of GZMB expression in human liver.
Western Blot (Tissue lysate)
GZMB MaxPab rabbit polyclonal antibody. Western Blot analysis of GZMB expression in mouse kidney.
Western Blot (Transfected lysate)
Western Blot analysis of GZMB expression in transfected 293T cell line (H00003002-T03) by GZMB MaxPab polyclonal antibody.
Lane 1: GZMB transfected lysate(27.70 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GZMB protein.
Immunogen
GZMB (AAH30195.1, 1 a.a. ~ 247 a.a) full-length human protein.
Sequence
MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIQDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRH
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GZMB MaxPab rabbit polyclonal antibody. Western Blot analysis of GZMB expression in human liver.Western Blot (Tissue lysate)
GZMB MaxPab rabbit polyclonal antibody. Western Blot analysis of GZMB expression in mouse kidney.Western Blot (Transfected lysate)
Western Blot analysis of GZMB expression in transfected 293T cell line (H00003002-T03) by GZMB MaxPab polyclonal antibody.
Lane 1: GZMB transfected lysate(27.70 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GZMB
Entrez GeneID
3002GeneBank Accession#
BC030195Protein Accession#
AAH30195.1Gene Name
GZMB
Gene Alias
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Gene Description
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
Omim ID
123910Gene Ontology
HyperlinkGene Summary
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq
Other Designations
T-cell serine protease 1-3E|cathepsin G-like 1|cytotoxic serine protease B|fragmentin 2|granzyme B
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Interactome
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Pathway
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Disease
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Publication Reference
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Granzyme B is a novel interleukin-18 converting enzyme.
Omoto Y, Yamanaka K, Tokime K, Kitano S, Kakeda M, Akeda T, Kurokawa I, Gabazza EC, Tsutsui H, Katayama N, Yamanishi K, Nakanishi K, Mizutani H.
Journal of Dermatological Science 2010 Aug; 59(2):129.
Application：WB-Ce, Human, T cells, THP-1 cells.
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Granzyme B is a novel interleukin-18 converting enzyme.
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