GSN MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human GSN protein.
Immunogen
GSN (AAH26033.1, 1 a.a. ~ 782 a.a) full-length human protein.
Sequence
MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAELAA
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GSN MaxPab rabbit polyclonal antibody. Western Blot analysis of GSN expression in human liver.Western Blot (Tissue lysate)
GSN MaxPab rabbit polyclonal antibody. Western Blot analysis of GSN expression in human pancreas.Western Blot (Cell lysate)
GSN MaxPab rabbit polyclonal antibody. Western Blot analysis of GSN expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of GSN expression in transfected 293T cell line (H00002934-T01) by GSN MaxPab polyclonal antibody.
Lane 1: GSN transfected lysate(85.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of GSN transfected lysate using anti-GSN MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with GSN purified MaxPab mouse polyclonal antibody (B01P) (H00002934-B01P). -
Gene Info — GSN
Entrez GeneID
2934GeneBank Accession#
BC026033.1Protein Accession#
AAH26033.1Gene Name
GSN
Gene Alias
DKFZp313L0718
Gene Description
gelsolin (amyloidosis, Finnish type)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022011|OTTHUMP00000162202|gelsolin
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Interactome
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Pathway
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Disease
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