XRCC6 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of XRCC6 expression in transfected 293T cell line (H00002547-T01) by XRCC6 MaxPab polyclonal antibody.
Lane 1: XRCC6 transfected lysate(69.80 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of XRCC6 transfected lysate using anti-XRCC6 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with XRCC6 MaxPab rabbit polyclonal antibody (D01) (H00002547-D01).
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to XRCC6 on HeLa cell. [antibody concentration 5 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human XRCC6 protein.
Immunogen
XRCC6 (NP_001460.1, 1 a.a. ~ 609 a.a) full-length human protein.
Sequence
MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPFDMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELDQFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDSAKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLEDLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKTRTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (83)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of XRCC6 expression in transfected 293T cell line (H00002547-T01) by XRCC6 MaxPab polyclonal antibody.
Lane 1: XRCC6 transfected lysate(69.80 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of XRCC6 transfected lysate using anti-XRCC6 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with XRCC6 MaxPab rabbit polyclonal antibody (D01) (H00002547-D01).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to XRCC6 on HeLa cell. [antibody concentration 5 ug/ml] -
Gene Info — XRCC6
Entrez GeneID
2547GeneBank Accession#
NM_001469Protein Accession#
NP_001460.1Gene Name
XRCC6
Gene Alias
CTC75, CTCBF, G22P1, KU70, ML8, TLAA
Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 6
Omim ID
152690Gene Ontology
HyperlinkGene Summary
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq
Other Designations
ATP-dependent DNA helicase II, 70 kDa subunit|CTC box binding factor 75 kDa subunit|Ku autoantigen p70 subunit|Ku autoantigen, 70kDa|OTTHUMP00000028581|thyroid autoantigen 70kD (Ku antigen)|thyroid autoantigen 70kDa (Ku antigen)|thyroid-lupus autoantigen
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Interactome
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Pathway
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Disease
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