F11 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
F11 MaxPab rabbit polyclonal antibody. Western Blot analysis of F11 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of F11 expression in transfected 293T cell line (H00002160-T01) by F11 MaxPab polyclonal antibody.
Lane 1: F11 transfected lysate(70.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of F11 transfected lysate using anti-F11 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with F11 purified MaxPab mouse polyclonal antibody (B01P) (H00002160-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human F11 protein.
Immunogen
F11 (NP_000119.1, 1 a.a. ~ 625 a.a) full-length human protein.
Sequence
MIFLYQVVHFILFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLFTFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLDMKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRITKLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFFTFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDTDFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKILHGRGGISGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQAV
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
F11 MaxPab rabbit polyclonal antibody. Western Blot analysis of F11 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of F11 expression in transfected 293T cell line (H00002160-T01) by F11 MaxPab polyclonal antibody.
Lane 1: F11 transfected lysate(70.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of F11 transfected lysate using anti-F11 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with F11 purified MaxPab mouse polyclonal antibody (B01P) (H00002160-B01P). -
Gene Info — F11
Entrez GeneID
2160GeneBank Accession#
NM_000128.2Protein Accession#
NP_000119.1Gene Name
F11
Gene Alias
FXI, MGC141891
Gene Description
coagulation factor XI
Omim ID
264900Gene Ontology
HyperlinkGene Summary
This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq
Other Designations
plasma thromboplastin antecedent|platelet coagulation factor XI
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Interactome
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Pathway
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Disease
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