DSCR1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
DSCR1 transfected lysate.
Western Blot
Lane 1: DSCR1 transfected lysate ( 13.3 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-DSCR1 full-length
Host
Human
Theoretical MW (kDa)
13.3
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-DSCR1 antibody (H00001827-B01) by Western Blots.
SDS-PAGE Gel
DSCR1 transfected lysate.
Western Blot
Lane 1: DSCR1 transfected lysate ( 13.3 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — RCAN1
Entrez GeneID
1827GeneBank Accession#
NM_203417.1Protein Accession#
-Gene Name
RCAN1
Gene Alias
ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Gene Description
regulator of calcineurin 1
Omim ID
602917Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Down syndrome candidate region 1|Down syndrome critical region gene 1|calcipressin 1|calcium and oxidant-inducible mRNA|modulatory calcineurin-interacting protein 1|myocyte-enriched calcineurin-interacting protein 1|near DSCR proline-rich protein
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Interactome
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Disease
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