CYP11B1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CYP11B1 full-length
Host
Human
Theoretical MW (kDa)
63.25
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CYP11B1 antibody (H00001584-B01) by Western Blots.
SDS-PAGE Gel
CYP11B1 transfected lysate.
Western Blot
Lane 1: CYP11B1 transfected lysate ( 63.25 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CYP11B1
Entrez GeneID
1584GeneBank Accession#
BC096285.3Protein Accession#
AAH96285.1Gene Name
CYP11B1
Gene Alias
CPN1, CYP11B, DKFZp686B05283, FHI, FLJ36771, P450C11
Gene Description
cytochrome P450, family 11, subfamily B, polypeptide 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
Other Designations
cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1|cytochrome p450 XIB1|steroid 11-beta-hydroxylase|steroid 11-beta-monooxygenase
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