CSE1L monoclonal antibody (M07A), clone 1C4
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More Files
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Western Blot (Cell lysate)
CSE1L monoclonal antibody (M07A), clone 1C4 Western Blot analysis of CSE1L expression in HeLa ( Cat # L013V1 ).
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CSE1L.
Immunogen
CSE1L (NP_001307, 872 a.a. ~ 971 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LIGLFELPEDDTIPDEEHFIDIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQGYLQAARVTLL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (92)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CSE1L monoclonal antibody (M07A), clone 1C4 Western Blot analysis of CSE1L expression in HeLa ( Cat # L013V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — CSE1L
Entrez GeneID
1434GeneBank Accession#
NM_001316Protein Accession#
NP_001307Gene Name
CSE1L
Gene Alias
CAS, CSE1, MGC117283, MGC130036, MGC130037, XPO2
Gene Description
CSE1 chromosome segregation 1-like (yeast)
Omim ID
601342Gene Ontology
HyperlinkGene Summary
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq
Other Designations
CSE1 chromosome segregation 1-like protein|OTTHUMP00000043373|cellular apoptosis susceptibility protein|chromosome segregation 1-like|importin-alpha re-exporter
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