CRX monoclonal antibody (M06), clone 4A12
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CRX expression in transfected 293T cell line by CRX monoclonal antibody (M06), clone 4A12.
Lane 1: CRX transfected lysate(32.3 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of monoclonal antibody to CRX on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (58.63 KDa) .
-
Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant CRX.
Immunogen
CRX (AAH16664, 1 a.a. ~ 299 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (58.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Transfected lysate)
Western Blot analysis of CRX expression in transfected 293T cell line by CRX monoclonal antibody (M06), clone 4A12.
Lane 1: CRX transfected lysate(32.3 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to CRX on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — CRX
Entrez GeneID
1406GeneBank Accession#
BC016664Protein Accession#
AAH16664Gene Name
CRX
Gene Alias
CORD2, CRD, LCA7, OTX3
Gene Description
cone-rod homeobox
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
cone-rod homeobox protein|orthodenticle homeobox 3
-
Interactome
-
Disease
-
Publication Reference
-
Aberrant hiPSCs-Derived from Human Keratinocytes Differentiates into 3D Retinal Organoids that Acquire Mature Photoreceptors.
Shrestha R, Wen YT, Ding DC, Tsai RK.
Cells 2019 Jan; 8(1):E36.
Application：IF, Human, hiPSC-derived 3-D retinal organoids.
-
Aberrant hiPSCs-Derived from Human Keratinocytes Differentiates into 3D Retinal Organoids that Acquire Mature Photoreceptors.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com