CDKN2B 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-CDKN2B full-length
Host
Human
Theoretical MW (kDa)
15.29
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CDKN2B antibody (H00001030-B02) by Western Blots.
SDS-PAGE Gel
CDKN2B transfected lysate.
Western Blot
Lane 1: CDKN2B transfected lysate ( 15.29 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — CDKN2B
Entrez GeneID
1030GeneBank Accession#
BC014469Protein Accession#
AAH14469Gene Name
CDKN2B
Gene Alias
CDK4I, INK4B, MTS2, P15, TP15, p15INK4b
Gene Description
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Omim ID
600431Gene Ontology
HyperlinkGene Summary
This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
Other Designations
CDK inhibitory protein|CDK4B inhibitor|OTTHUMP00000021154|OTTHUMP00000021155|cyclin-dependent kinase 4 inhibitor B|cyclin-dependent kinase inhibitor 2B|cyclin-dependent kinases 4 and 6 binding protein|multiple tumor suppressor 2|p14_CDK inhibitor|p14_INK4
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com