CDKN1C polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CDKN1C.
Immunogen
CDKN1C (NP_000067, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.
Sequence
MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRETVQVGRC
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CDKN1C
Entrez GeneID
1028GeneBank Accession#
NM_000076Protein Accession#
NP_000067Gene Name
CDKN1C
Gene Alias
BWCR, BWS, KIP2, WBS, p57
Gene Description
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011736|cyclin-dependent kinase inhibitor 1C
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Interactome
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Pathway
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Disease
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