CD70 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CD70 expression in transfected 293T cell line (H00000970-T01) by CD70 MaxPab polyclonal antibody.
Lane 1: CD70 transfected lysate(21.23 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CD70 protein.
Immunogen
CD70 (NP_001243, 1 a.a. ~ 193 a.a) full-length human protein.
Sequence
MPEEGSGCSVRRRPYGCVLRAALVPLVAGLVICLVVCIQRFAQAQQQLPLESLGWDVAELQLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTASRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRNTDETFFGVQWVRP
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CD70 expression in transfected 293T cell line (H00000970-T01) by CD70 MaxPab polyclonal antibody.
Lane 1: CD70 transfected lysate(21.23 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CD70
Entrez GeneID
970GeneBank Accession#
NM_001252Protein Accession#
NP_001243Gene Name
CD70
Gene Alias
CD27L, CD27LG, TNFSF7
Gene Description
CD70 molecule
Omim ID
602840Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq
Other Designations
CD27 ligand|CD70 antigen|Ki-24 antigen|surface antigen CD70|tumor necrosis factor (ligand) superfamily, member 7|tumor necrosis factor ligand superfamily, member 7
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Interactome
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Pathway
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Disease
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