CD68 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
CD68 transfected lysate.
Western Blot
Lane 1: CD68 transfected lysate ( 37.4 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CD68 full-length
Host
Human
Theoretical MW (kDa)
37.4
Interspecies Antigen Sequence
Rat (74)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CD68 antibody (H00000968-B01) by Western Blots.
SDS-PAGE Gel
CD68 transfected lysate.
Western Blot
Lane 1: CD68 transfected lysate ( 37.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CD68
Entrez GeneID
968GeneBank Accession#
NM_001251.2Protein Accession#
NP_001242.2Gene Name
CD68
Gene Alias
DKFZp686M18236, GP110, SCARD1
Gene Description
CD68 molecule
Omim ID
153634Gene Ontology
HyperlinkGene Summary
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq
Other Designations
CD68 antigen|OTTHUMP00000135285|macrophage antigen CD68|macrosialin|scavenger receptor class D, member 1
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