CBL (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of CBL transfected lysate using mouse monoclonal anti-CBL and Protein A Magnetic Bead (U0007), and immunoblotted with mouse monoclonal anti-CBL.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of CBL transfected lysate using mouse monoclonal anti-CBL and Protein A Magnetic Bead (U0007), and immunoblotted with mouse monoclonal anti-CBL.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-CBL (300 ug)
2. Antibody pair for WB: mouse monoclonal anti-CBL (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — CBL
Entrez GeneID
867Gene Name
CBL
Gene Alias
C-CBL, CBL2, RNF55
Gene Description
Cas-Br-M (murine) ecotropic retroviral transforming sequence
Omim ID
165360Gene Ontology
HyperlinkGene Summary
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq
Other Designations
oncogene CBL2
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Interactome
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Pathway
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Disease
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