CACNB2 monoclonal antibody (M05), clone 6C4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CACNB2.
Immunogen
CACNB2 (NP_963890, 213 a.a. ~ 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQ
Host
Mouse
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.53 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CACNB2 monoclonal antibody (M05), clone 6C4 Western Blot analysis of CACNB2 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Cell lysate)
CACNB2 monoclonal antibody (M05), clone 6C4. Western Blot analysis of CACNB2 expression in NIH/3T3 ( Cat # L018V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CACNB2 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — CACNB2
Entrez GeneID
783GeneBank Accession#
NM_201596Protein Accession#
NP_963890Gene Name
CACNB2
Gene Alias
CACNLB2, CAVB2, FLJ23743, MYSB
Gene Description
calcium channel, voltage-dependent, beta 2 subunit
Omim ID
600003Gene Ontology
HyperlinkGene Summary
voltage-dependent
Other Designations
OTTHUMP00000019254|OTTHUMP00000019255|OTTHUMP00000019256|OTTHUMP00000196786|myasthenic (Lambert-Eaton) syndrome antigen B
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Interactome
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Pathway
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Disease
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Publication Reference
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Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes.
Horiuchi-Hirose M, Kashihara T, Nakada T, Kurebayashi N, Shimojo H, Shibazaki T, Sheng X, Yano S, Hirose M, Hongo M, Sakurai T, Moriizumi T, Ueda H, Yamada M.
American Journal of Physiology. Heart and Circulatory Physiology 2011 Mar; 300(3):H978.
Application:WB-Ti, Mouse, Mouse hearts.
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Role of glycine residues highly conserved in the S2-S3 linkers of domains I and II of voltage-gated calcium channel alpha1 subunits.
Teng J, Iida K, Ito M, Izumi-Nakaseko H, Kojima I, Adachi-Akahane S, Iida H.
Biochimica et Biophysica Acta 2010 May; 1798(5):966.
Application:WB-Tr, Human, tsA201 cells.
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Decrease in the density of t-tubular L-type Ca2+ channel currents in failing ventricular myocytes.
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