BMX monoclonal antibody (M01), clone 3G3
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of BMX expression in transfected 293T cell line by BMX monoclonal antibody (M01), clone 3G3.
Lane 1: BMX transfected lysate (Predicted MW: 78.011 KDa).
Lane 2: Non-transfected lysate.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged BMX is 0.03 ng/ml as a capture antibody.
Western Blot detection against Immunogen (40.15 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant BMX.
Immunogen
BMX (AAH16652, 150 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ANLHTAVNEEKHRVPTFPDRVLKIPRAVPVLKMDAPSSSTTLAQYDNESKKNYGSQPPSSSTSLAQYDSNSKKIYGSQPNFNMQYIPREDFPDWWQVRKLKSSSSSEDVASSNQKERNVNHTTSKISWEFP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (58); Rat (55)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (40.15 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of BMX expression in transfected 293T cell line by BMX monoclonal antibody (M01), clone 3G3.
Lane 1: BMX transfected lysate (Predicted MW: 78.011 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged BMX is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — BMX
Entrez GeneID
660GeneBank Accession#
BC016652Protein Accession#
AAH16652Gene Name
BMX
Gene Alias
ETK, PSCTK2, PSCTK3
Gene Description
BMX non-receptor tyrosine kinase
Omim ID
300101Gene Ontology
HyperlinkGene Summary
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified
Other Designations
OTTHUMP00000022964|OTTHUMP00000022965|OTTHUMP00000022966
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Interactome
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Disease
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