BMP7 monoclonal antibody (M01), clone M1-F8
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More Files
- More Functions
Western Blot (Tissue lysate)
BMP7 monoclonal antibody (M01), clone M1-F8. Western Blot analysis of BMP7 expression in human uterus myoma.
Western Blot (Cell lysate)
BMP7 monoclonal antibody (M01), clone M1-F8. Western Blot analysis of BMP7 expression in A-549 ( Cat # L025V1 ).
Western Blot (Cell lysate)
BMP7 monoclonal antibody (M01), clone M1-F8. Western Blot analysis of BMP7 expression in Raw 264.7.
Western Blot (Transfected lysate)
Western Blot analysis of BMP7 expression in transfected 293T cell line by BMP7 monoclonal antibody (M01), clone M1-F8.
Lane 1: BMP7 transfected lysate(49.313 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (73.15 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant BMP7.
Immunogen
BMP7 (AAH08584, 1 a.a. ~ 431 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MHVRSLRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRPRPHLQGKHNSAPMFMLDLYNAMAVEEGGGPGGQGFSYPYKAVFSTQGPPLASLQDSHFLTDADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFDNETFRISVYQVLQEHLGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQSINPKLAGLIGRHGPQNKQPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH
Host
Mouse
Reactivity
Human, Mouse
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (73.15 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
BMP7 monoclonal antibody (M01), clone M1-F8. Western Blot analysis of BMP7 expression in human uterus myoma.Western Blot (Cell lysate)
BMP7 monoclonal antibody (M01), clone M1-F8. Western Blot analysis of BMP7 expression in A-549 ( Cat # L025V1 ).Western Blot (Cell lysate)
BMP7 monoclonal antibody (M01), clone M1-F8. Western Blot analysis of BMP7 expression in Raw 264.7.Western Blot (Transfected lysate)
Western Blot analysis of BMP7 expression in transfected 293T cell line by BMP7 monoclonal antibody (M01), clone M1-F8.
Lane 1: BMP7 transfected lysate(49.313 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — BMP7
Entrez GeneID
655GeneBank Accession#
BC008584Protein Accession#
AAH08584Gene Name
BMP7
Gene Alias
OP-1
Gene Description
bone morphogenetic protein 7
Omim ID
112267Gene Ontology
HyperlinkGene Summary
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq
Other Designations
OTTHUMP00000031357|osteogenic protein 1
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Interactome
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Pathway
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Disease
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Publication Reference
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BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure.
Loureiro J, Schilte M, Aguilera A, Albar-Vizcaino P, Ramirez-Huesca M, Perez-Lozano LM, Gonzalez-Mateo G, Aroeira LS, Selgas R, Mendoza L, Ortiz A, Ruiz-Ortega M, van den Born J, Beelen RH, Lopez-Cabrera M.
Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis 2010 Apr; 25(4):1098.
Application：ELISA, Human, Mesothelial cells.
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BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure.
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