TNFRSF17 monoclonal antibody (M09), clone 8B4
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More Files
- More Functions
Western Blot detection against Immunogen (31.13 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TNFRSF17.
Immunogen
TNFRSF17 (AAH58291.1, 5 a.a. ~ 50 a.a) partial recombinant protein with mouse IgG2a-Fc tag.
Sequence
AGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (70); Rat (61)
Isotype
IgG2a Lambda
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (31.13 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — TNFRSF17
Entrez GeneID
608GeneBank Accession#
BC058291.1Protein Accession#
AAH58291.1Gene Name
TNFRSF17
Gene Alias
BCM, BCMA, CD269
Gene Description
tumor necrosis factor receptor superfamily, member 17
Omim ID
109545Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq
Other Designations
B cell maturation antigen|B-cell maturation factor|OTTHUMP00000160261
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Interactome
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Pathway
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Disease
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