PHOX2A purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of PHOX2A expression in transfected 293T cell line (H00000401-T01) by PHOX2A MaxPab polyclonal antibody.
Lane 1: PHOX2A transfected lysate(31.24 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PHOX2A on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PHOX2A protein.
Immunogen
PHOX2A (NP_005160.2, 1 a.a. ~ 284 a.a) full-length human protein.
Sequence
MDYSYLNSYDSCVAAMEASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQPAPYSAVPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAAELLKAWQPAESGPGPFSGVLSSFHRKPGPALKTNLF
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PHOX2A expression in transfected 293T cell line (H00000401-T01) by PHOX2A MaxPab polyclonal antibody.
Lane 1: PHOX2A transfected lysate(31.24 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PHOX2A on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — PHOX2A
Entrez GeneID
401GeneBank Accession#
NM_005169.2Protein Accession#
NP_005160.2Gene Name
PHOX2A
Gene Alias
ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
Gene Description
paired-like homeobox 2a
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq
Other Designations
aristaless homeobox homolog|arix homeodomain protein
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Interactome
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Disease
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