ADRB2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and ADRB2 expressing 293 cells (Green) using ADRB2 purified MaxPab mouse polyclonal antibody.
Western Blot (Transfected lysate)
Western Blot analysis of ADRB2 expression in transfected 293T cell line (H00000154-T02) by ADRB2 MaxPab polyclonal antibody.
Lane 1: ADRB2 transfected lysate(45.43 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ADRB2 protein.
Immunogen
ADRB2 (NP_000015, 1 a.a. ~ 413 a.a) full-length human protein.
Sequence
MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (87)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and ADRB2 expressing 293 cells (Green) using ADRB2 purified MaxPab mouse polyclonal antibody.Western Blot (Transfected lysate)
Western Blot analysis of ADRB2 expression in transfected 293T cell line (H00000154-T02) by ADRB2 MaxPab polyclonal antibody.
Lane 1: ADRB2 transfected lysate(45.43 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ADRB2
Entrez GeneID
154GeneBank Accession#
NM_000024Protein Accession#
NP_000015Gene Name
ADRB2
Gene Alias
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Gene Description
adrenergic, beta-2-, receptor, surface
Gene Ontology
HyperlinkGene Summary
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq
Other Designations
beta-2 adrenergic receptor|beta-2 adrenoceptor|catecholamine receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification of novel competing β2AR phospho-extracellular signal regulated kinase 1/2 signaling pathways in human trabecular meshwork cells.
Hudson BD, Kelly ME.
Journal of Ocular Pharmacology and Therapeutics 2012 Feb; 28(1):17.
Application：IF, Human, Human trabecular meshwork cells.
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Changes and role of adrenoceptors in PC12 cells after phenylephrine administration and apoptosis induction.
Lencesova L, Sirova M, Csaderova L, Laukova M, Sulova Z, Kvetnansky R, Krizanova O.
Neurochemistry International 2010 Dec; 57(8):884.
Application：IF, WB-Ce, Rat, PC-12 cells.
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Identification of novel competing β2AR phospho-extracellular signal regulated kinase 1/2 signaling pathways in human trabecular meshwork cells.
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