PLS3/CENXp FISH Probe
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More Files
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DNA Hybridization
Human Lung adenocarcinoma cells stained with PLS3/CENXp FISH Probe shows the PLS3 copy number gain.
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique.
Probe 1
Name: PLS3
Size: Approximately 170 kb
Fluorophore: Texas Red
Location: Xq23Probe 2
Name: CENXp
Size: Approximately 400 kb
Fluorophore: FITC
Location: Xp11.22Probe Gap
The gap between two probes is approximately 5,790 kb
Origin
Human
Source
Genomic DNA
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome.
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Applications
DNA Hybridization
Human Lung adenocarcinoma cells stained with PLS3/CENXp FISH Probe shows the PLS3 copy number gain. -
Gene Info — PLS3
Entrez GeneID
5358Gene Name
PLS3
Gene Alias
T-plastin
Gene Description
plastin 3 (T isoform)
Omim ID
300131Gene Ontology
HyperlinkGene Summary
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
T isoform|T plastin|plastin 3
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