1p36.33/CEN1p FISH Probe
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Specification
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology).
Probe 1
Name: 1p36.33
Size: Approximately 600kb
Fluorophore: Texas Red
Location: 1p36.33Probe 2
Name: CEN1p
Size: Approximately 780kb
Fluorophore: FITC
Location: 1p13.3Probe Gap
The gap between two probes is approximately 107,700 kb.
Origin
Human
Source
Genomic DNA
Reactivity
Human
Form
Liquid
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Regulation Status
For research use only (RUO)
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product
DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome. -
Applications
Fluorescent In Situ Hybridization (Cell)
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Human colon cancer (FFPE) stained with 1p36.33/CEN1p FISH Probe. Human colon cancer showed no 1p36.33 gene amplification -
Publication Reference
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Genomic gains and losses in malignant mesothelioma demonstrated by FISH analysis of paraffin-embedded tissues.
Takeda M, Kasai T, Enomoto Y, Takano M, Morita K, Kadota E, Iizuka N, Maruyama H, Nonomura A.
Journal of Clinical Pathology 2012 Jan; 65(1):77.
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Genomic gains and losses in malignant mesothelioma demonstrated by FISH analysis of paraffin-embedded tissues.
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