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BIOtech
BULK-new

ILK polyclonal antibody

  • Catalog # : PAB8785
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ILK.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human ILK.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 59
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody recognizes 59 KDa of ILK1.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.5-4 ug/mL)
    Immunohistochemistry (Frozen sections) (10-20 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10-20 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (30% glycerol, 0.5% BSA, 0.01% thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of ILK in Jurkat cell lysate (Lane 1&2) and rat kidney tissue lysate (Lane 3) .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 3611
  • Gene Name:
  • ILK
  • Gene Alias:
  • DKFZp686F1765,P59
  • Gene Description:
  • integrin-linked kinase
  • Gene Summary:
  • Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
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