ADORA2B polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of ADORA2B.
Immunogen
A synthetic peptide corresponding to human ADORA2B.
Sequence
CQADVKSGNGQ
Host
Goat
Theoretical MW (kDa)
36.3
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:4000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
ADORA2B polyclonal antibody (Cat # PAB6870) (2 ug/mL) staining of paraffin embedded human kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ADORA2B
Entrez GeneID
136Protein Accession#
NP_000667.1Gene Name
ADORA2B
Gene Alias
ADORA2
Gene Description
adenosine A2b receptor
Omim ID
600446Gene Ontology
HyperlinkGene Summary
This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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Publication Reference
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Mechanisms involved in the adenosine-induced vasorelaxation to the pig prostatic small arteries.
Ribeiro AS, Fernandes VS, Orensanz LM, Martinez MP, Recio P, Martinez-Saenz A, Climent B, Arteaga JL, Garcia-Sacristan A, Prieto D, Hernandez M.
Purinergic Signalling 2011 Dec; 7(4):413.
Application:WB-Ti, Pig, Prostatic small arteries.
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A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis.
Bazzichi L, Trincavelli L, Rossi A, De Feo F, Lucacchini A, Bombardieri S, Martini C.
Arthritis Research & Therapy 2005 Dec; 7(2):R189.
Application:WB-Ce, Human, Human neutrophils.
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Mechanisms involved in the adenosine-induced vasorelaxation to the pig prostatic small arteries.
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