BCOR polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of BCOR.
Immunogen
A synthetic peptide corresponding to human BCOR.
Sequence
LSATPLYGNVHSW-C
Host
Goat
Theoretical MW (kDa)
188, 186, 192
Specificity
This antibody is expected to recognize both reported isoforms (represented by NP_060215 and NP_065977).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
ChIP
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — BCOR
Entrez GeneID
54880Protein Accession#
NP_060215;NP_065977Gene Name
BCOR
Gene Alias
ANOP2, FLJ20285, FLJ38041, KIAA1575, MAA2, MCOPS2, MGC131961, MGC71031
Gene Description
BCL6 co-repressor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
5830466J11Rik|8430401K06Rik|BCL-6 interacting corepressor|OTTHUMP00000025766|OTTHUMP00000025768
-
Interactome
-
Publication Reference
-
The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor.
Tang TT, Dowbenko D, Jackson A, Toney L, Lewin DA, Dent AL, Lasky LA.
The Journal of Biological Chemistry 2002 Apr; 277(16):14255.
-
The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com