The AK3L1 polyclonal antibody (Cat # PAB3988) is used in Western blot to detect AK3L1 in mouse kidney tissue lysate.
Western Blot (Transfected lysate)
Western blot analysis of AK3L1 (arrow) using rabbit AK3L1 polyclonal antibody (Cat # PAB3988). 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AK3L1 gene (Lane 2) (Origene Technologies).
Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with AK3L1 polyclonal antibody (Cat # PAB3988) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq