TCIRG1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of TCIRG1 in EL4 cell lysate with TCIRG1 polyclonal antibody (Cat # PAB25649) at 0.5 ug/ml in (1) the absence and (2) the presence of blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TCIRG1.
Immunogen
A synthetic peptide corresponding to 19 amino acids at N-terminus of human TCIRG1.
Host
Rabbit
Theoretical MW (kDa)
91
Reactivity
Human, Mouse, Rat
Specificity
At least two alternatively spliced isoforms are known to exist; this antibody will only detect the larger isoform.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TCIRG1 in EL4 cell lysate with TCIRG1 polyclonal antibody (Cat # PAB25649) at 0.5 ug/ml in (1) the absence and (2) the presence of blocking peptide.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TCIRG1
Entrez GeneID
10312Protein Accession#
NP_006010Gene Name
TCIRG1
Gene Alias
ATP6N1C, ATP6V0A3, Atp6i, OC-116kDa, OC116, OPTB1, Stv1, TIRC7, Vph1, a3
Gene Description
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
Gene Ontology
HyperlinkGene Summary
Through alternate splicing, this gene encodes two proteins with similarity to subunits of the vacuolar ATPase (V-ATPase) but the encoded proteins seem to have different functions. V-ATPase is a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Mutations in this gene are associated with infantile malignant osteopetrosis. [provided by RefSeq
Other Designations
ATPase, H+ transporting, 116kD|T cell immune response cDNA7 protein|T-cell immune regulator 1|T-cell, immune regulator 1|T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3|T-cell, immune regulator 1, ATPase, H+ transporting, lyso
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Interactome
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Pathway
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Disease
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