ACTL6B polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of human fetal skeletal muscle lysate with ACTL6B polyclonal antibody (Cat # PAB18532) at 1 : 500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant ACTL6B.
Immunogen
Recombinant protein corresponding to amino acids 178-452 of human ACTL6B.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to ACTL6B.
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000-1:2000)
ELISA (1:10000-1:80000)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of human fetal skeletal muscle lysate with ACTL6B polyclonal antibody (Cat # PAB18532) at 1 : 500 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ACTL6B
Entrez GeneID
51412GeneBank Accession#
BC020944Gene Name
ACTL6B
Gene Alias
ACTL6, BAF53B
Gene Description
actin-like 6B
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. [provided by RefSeq
Other Designations
53 kDa BRG1-associated factor B|actin-like 6|actin-related protein|hArpN alpha
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Interactome
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Disease
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Publication Reference
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA,
PNAS 2002 Dec; 99(26):16899.
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
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