ADCY4 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from Jurkat cells, using ADCY4 polyclonal antibody (Cat # PAB17484).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ADCY4.
Immunogen
A synthetic peptide corresponding to internal of human ADCY4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of total ADCY4 protein.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (without Mg2+ and Ca2+), pH 7.4 (15 0mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from Jurkat cells, using ADCY4 polyclonal antibody (Cat # PAB17484).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — ADCY4
Entrez GeneID
196883Protein Accession#
Q8NFM4Gene Name
ADCY4
Gene Alias
AC4
Gene Description
adenylate cyclase 4
Omim ID
600292Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. [provided by RefSeq
Other Designations
adenylate cyclase type IV
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Pathway
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Disease
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Publication Reference
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Adenylyl Cyclase 1 as a Major Isoform to Generate cAMP Signaling for ApoA-1-mediated Cholesterol Efflux Pathway.
Tang W, Ma W, Ding H, Lin M, Xiang L, Lin G, Zhang Z.
Journal of Lipid Research 2018 Apr; 59(4):635.
Application：WB-Ce, Human, THP-1 macrophages-derived foam cells.
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Adenylyl Cyclase 1 as a Major Isoform to Generate cAMP Signaling for ApoA-1-mediated Cholesterol Efflux Pathway.
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