AGTR2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of AGTR2 in mouse liver tissue lysate with AGTR2 polyclonal antibody (Cat # PAB16829) at 0.5 ug/mL .
Immunohistochemistry
Immunohistochemical staining of rat liver tissue with 5 ug/mL AGTR2 polyclonal antibody (Cat # PAB16829).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AGTR2.
Immunogen
A synthetic peptide corresponding to internal region 16 amino acids of human AGTR2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of AGTR2 in mouse liver tissue lysate with AGTR2 polyclonal antibody (Cat # PAB16829) at 0.5 ug/mL .Immunohistochemistry
Immunohistochemical staining of rat liver tissue with 5 ug/mL AGTR2 polyclonal antibody (Cat # PAB16829).Enzyme-linked Immunoabsorbent Assay
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Gene Info — AGTR2
Entrez GeneID
186Protein Accession#
AAS45437Gene Name
AGTR2
Gene Alias
AT2, ATGR2, MRX88
Gene Description
angiotensin II receptor, type 2
Omim ID
300034Gene Ontology
HyperlinkGene Summary
Angiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5' untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame. [provided by RefSeq
Other Designations
OTTHUMP00000023878|angiotensin receptor 2
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Interactome
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