SNPH polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of SNPH in human brain tissue lysate with SNPH polyclonal antibody (Cat # PAB13375) at (A) 2 and (B) 4 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of SNPH in human brain with SNPH polyclonal antibody (Cat # PAB13375) at 5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SNPH.
Immunogen
A synthetic peptide corresponding to N-terminus 18 amino acids of human SNPH.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SNPH in human brain tissue lysate with SNPH polyclonal antibody (Cat # PAB13375) at (A) 2 and (B) 4 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of SNPH in human brain with SNPH polyclonal antibody (Cat # PAB13375) at 5 ug/mL . -
Gene Info — SNPH
Entrez GeneID
9751Protein Accession#
O15079Gene Name
SNPH
Gene Alias
KIAA0374, MGC46096, bA314N13.5
Gene Description
syntaphilin
Omim ID
604942Gene Ontology
HyperlinkGene Summary
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. [provided by RefSeq
Other Designations
OTTHUMP00000070985
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Interactome
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Publication Reference
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Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation.
Kang JS, Tian JH, Pan PY, Zald P, Li C, Deng C, Sheng ZH.
Cell 2008 Jan; 132(1):137.
Application：IF, Rat, Rat hippocampal neurons.
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Syntaphilin binds to dynamin-1 and inhibits dynamin-dependent endocytosis.
Das S, Gerwin C, Sheng ZH.
The Journal of Biological Chemistry 2003 Oct; 278(42):41221.
Application：IP, WB-Tr, Monkey, COS-7 cells.
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Syntaphilin: a syntaxin-1 clamp that controls SNARE assembly.
Lao G, Scheuss V, Gerwin CM, Su Q, Mochida S, Rettig J, Sheng ZH.
Neuron 2000 Jan; 25(1):191.
Application：IF, IP, WB-Ti, WB-Tr, Human, Rat, Synaptosomes, Brain, Heart, Kidney, Liver, Lung, Muscle, Spleen, HEK 293T cells.
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Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation.
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