ATG10 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of ATG10 in SK-N-SH cell lysate with ATG10 polyclonal antibody (Cat # PAB13017) at (A) 0.5, (B) 1 and (C) 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ATG10.
Immunogen
A synthetic peptide corresponding to C-terminus 15 amino acids of human ATG10.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of ATG10 in SK-N-SH cell lysate with ATG10 polyclonal antibody (Cat # PAB13017) at (A) 0.5, (B) 1 and (C) 2 ug/mL . -
Gene Info — ATG10
Entrez GeneID
83734Protein Accession#
EAW95884Gene Name
ATG10
Gene Alias
APG10, APG10L, DKFZp586I0418, FLJ13954, pp12616
Gene Description
ATG10 autophagy related 10 homolog (S. cerevisiae)
Omim ID
610800Gene Ontology
HyperlinkGene Summary
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM
Other Designations
APG10 autophagy 10-like
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Interactome
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Disease
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Publication Reference
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Autophagy as a cell death and tumor suppressor mechanism.
Gozuacik D, Kimchi A.
Oncogene 2004 Apr; 23(16):2891.
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Tor-mediated induction of autophagy via an Apg1 protein kinase complex.
Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Ohsumi Y.
Journal of Cellular Biology 2000 Sep; 150(6):1507.
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Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.
Kisen GO, Tessitore L, Costelli P, Gordon PB, Schwarze PE, Baccino FM, Seglen PO.
Carcinogenesis 1993 Dec; 14(12):2501.
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Autophagy as a cell death and tumor suppressor mechanism.
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