CREB1 (phospho S133) polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunoprecipitation
The tissue lysate derived from rat brain was immunoprecipitated by CREB1 (phospho S133) polyclonal antibody (Cat # PAB12673), then immuno-blotted by the CREB1 (phospho S133) polyclonal antibody (Cat # PAB12617) at 1 : 500 (lane 1), Lane 2 : negative control.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of CREB1.
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding S133 of human CREB1.
Sequence
RPSYR
Host
Rabbit
Theoretical MW (kDa)
40
Reactivity
Human, Rat
Specificity
This antibody only recognizes ~40 KDa of human CREB1.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (0.1-1 ug/mL)
ELISA (0.01-0.1 ug/mL)
Immunoprecipitation (2-5 ug/mL)
Immunohistochemistry (1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In TBS, pH 7.2 (BSA, 10% Proclin300)
Storage Instruction
Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Immunoprecipitation
The tissue lysate derived from rat brain was immunoprecipitated by CREB1 (phospho S133) polyclonal antibody (Cat # PAB12673), then immuno-blotted by the CREB1 (phospho S133) polyclonal antibody (Cat # PAB12617) at 1 : 500 (lane 1), Lane 2 : negative control.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CREB1
Entrez GeneID
1385Gene Name
CREB1
Gene Alias
CREB, MGC9284
Gene Description
cAMP responsive element binding protein 1
Omim ID
123810Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
active transcription factor CREB|cAMP-response element-binding protein-1|transactivator protein
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Activation of cAMP-response-element-binding protein (CREB) after focal cerebral ischemia stimulates neurogenesis in the adult dentate gyrus.
Zhu DY, Lau L, Liu SH, Wei JS, Lu YM.
PNAS 2004 Jun; 101(25):9453.
Application：WB-Ti, Rat, Rat brain.
-
Activation of cAMP-response-element-binding protein (CREB) after focal cerebral ischemia stimulates neurogenesis in the adult dentate gyrus.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com